Compile Data Set for Download or QSAR
Found 62 of ki data for polymerid = 3890
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314865(CHEMBL4172616)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238185(US9394303, 57)copy SMILEScopy InChI
Affinity DataKi:  130nM ΔG°:  -9.39kcal/mole IC50: 670nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238190(US9394303, 16)copy SMILEScopy InChI
Affinity DataKi:  210nM ΔG°:  -9.10kcal/mole IC50: 1.11E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238186(US9394303, 58)copy SMILEScopy InChI
Affinity DataKi:  250nM ΔG°:  -9.00kcal/mole IC50: 1.28E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238181(US9394303, 8)copy SMILEScopy InChI
Affinity DataKi:  290nM ΔG°:  -8.91kcal/mole IC50: 1.52E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314860(CHEMBL4161200)copy SMILEScopy InChI
Affinity DataKi:  340nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314864(CHEMBL4172927)copy SMILEScopy InChI
Affinity DataKi:  460nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314859(CHEMBL4169123)copy SMILEScopy InChI
Affinity DataKi:  460nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238192(US9394303, 18)copy SMILEScopy InChI
Affinity DataKi:  490nM ΔG°:  -8.60kcal/mole IC50: 2.54E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314863(CHEMBL4162253)copy SMILEScopy InChI
Affinity DataKi:  490nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50315690(CHEMBL4177447)copy SMILEScopy InChI
Affinity DataKi:  560nMAssay Description:Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314870(CHEMBL4160019)copy SMILEScopy InChI
Affinity DataKi:  740nMAssay Description:Antagonist activity against Nicotinic acetylcholine receptor (nAChR) of isolated Frog rectus Abdominis MuscleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238187(US9394303, 59)copy SMILEScopy InChI
Affinity DataKi:  820nM ΔG°:  -8.30kcal/mole IC50: 4.27E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238196(US9394303, 62)copy SMILEScopy InChI
Affinity DataKi:  880nM ΔG°:  -8.26kcal/mole IC50: 4.51E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238184(US9394303, 56)copy SMILEScopy InChI
Affinity DataKi:  900nM ΔG°:  -8.24kcal/mole IC50: 4.68E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314874(CHEMBL4176611)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314862(CHEMBL4169534)copy SMILEScopy InChI
Affinity DataKi:  1.08E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238191(US9394303, 17)copy SMILEScopy InChI
Affinity DataKi:  1.21E+3nM ΔG°:  -8.07kcal/mole IC50: 6.30E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238195(US9394303, 61)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nM ΔG°:  -8.02kcal/mole IC50: 6.76E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314861(CHEMBL4177395)copy SMILEScopy InChI
Affinity DataKi:  1.38E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238180(US9394303, 7)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nM ΔG°:  -7.98kcal/mole IC50: 7.30E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238182(US9394303, 9)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nM ΔG°:  -7.98kcal/mole IC50: 7.30E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50357753(CHEMBL1916191)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB8287PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314855(CHEMBL4176314)copy SMILEScopy InChI
Affinity DataKi:  1.52E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238194(US9394303, 60)copy SMILEScopy InChI
Affinity DataKi:  1.53E+3nM ΔG°:  -7.93kcal/mole IC50: 7.97E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50357752(CHEMBL1916190)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB8287PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50357756(CHEMBL1916194)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB8287PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50357755(CHEMBL1916193)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB8287PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238183(US9394303, 10)copy SMILEScopy InChI
Affinity DataKi:  2.06E+3nM ΔG°:  -7.75kcal/mole IC50: 1.07E+4nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50315693(CHEMBL4166826)copy SMILEScopy InChI
Affinity DataKi:  2.07E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238193(US9394303, 55)copy SMILEScopy InChI
Affinity DataKi:  2.09E+3nM ΔG°:  -7.74kcal/mole IC50: 1.09E+4nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50315549(CHEMBL4175537)copy SMILEScopy InChI
Affinity DataKi:  2.25E+3nMAssay Description:Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238189(US9394303, 15)copy SMILEScopy InChI
Affinity DataKi:  2.39E+3nM ΔG°:  -7.66kcal/mole IC50: 1.24E+4nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50119(1-(3-chlorophenyl)-6-(2-furanyl)-3-methyl-4-pyrazo...)copy SMILEScopy InChI
Affinity DataKi:  2.64E+3nM ΔG°:  -7.60kcal/mole IC50: 1.37E+4nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238188(US9394303, 14)copy SMILEScopy InChI
Affinity DataKi:  3.32E+3nM ΔG°:  -7.47kcal/mole IC50: 1.73E+4nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238179(US9394303, 6)copy SMILEScopy InChI
Affinity DataKi:  3.54E+3nM ΔG°:  -7.43kcal/mole IC50: 1.84E+4nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314877(CHEMBL4171691)copy SMILEScopy InChI
Affinity DataKi:  3.55E+3nMAssay Description:Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314947(CHEMBL4175134)copy SMILEScopy InChI
Affinity DataKi:  3.60E+3nMAssay Description:Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM96413(6-(2-furanyl)-3-methyl-1-phenyl-4-pyrazolo[3,4-b]p...)copy SMILEScopy InChI
Affinity DataKi:  4.25E+3nM ΔG°:  -7.32kcal/mole IC50: 2.21E+4nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314873(CHEMBL4174087)copy SMILEScopy InChI
Affinity DataKi:  4.46E+3nMAssay Description:Antagonist activity against Nicotinic acetylcholine receptor (nAChR) of isolated Frog rectus Abdominis MuscleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314876(CHEMBL4163814)copy SMILEScopy InChI
Affinity DataKi:  4.74E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314866(CHEMBL4161959)copy SMILEScopy InChI
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314854(CHEMBL4165700)copy SMILEScopy InChI
Affinity DataKi:  5.92E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314875(CHEMBL4168747)copy SMILEScopy InChI
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314884(CHEMBL4167271)copy SMILEScopy InChI
Affinity DataKi:  6.83E+3nMAssay Description:Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50314869(CHEMBL4167274)copy SMILEScopy InChI
Affinity DataKi:  8.38E+3nMAssay Description:Antagonist activity against Nicotinic acetylcholine receptor (nAChR) of isolated Frog rectus Abdominis MuscleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM21434(N-Benylpiperazine derivative, 23j | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB8287PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50357754(CHEMBL1916192)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB8287PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50315670(CHEMBL4164915)copy SMILEScopy InChI
Affinity DataKi:  1.37E+4nMAssay Description:Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TRWPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM238177(US9394303, 4)copy SMILEScopy InChI
Affinity DataKi:  1.46E+4nM ΔG°:  -6.59kcal/mole IC50: 7.57E+4nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HCMUS Patent
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